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Tetramisole Powder

Tetramisole Powder

Appearance: White Crystal Powder
Specification: NLT99%
CAS: 5086-74-8
Molecular Formula: C11H13ClN2S
Molecular Weight: 240.75
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package, Capsules)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of tetramisole powder in China. We warmly welcome yuo to wholesale bulk tetramisole powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Tetramisole HCl

Tetramisole powder is a medication that has both anthelmintic (anti-parasitic) and immunomodulatory properties. It is primarily used in veterinary medicine to treat parasitic infestations in animals, especially in livestock.

 

Tetramisole HCl is effective against a wide range of parasites, including roundworms, hookworms, and lungworms. It works by inhibiting the enzyme acetylcholinesterase, which leads to paralysis and subsequent death of the parasites. By targeting the nervous system of the parasites, tetramisole HCl helps to eliminate them from the animal's body.

 

In addition to its anthelmintic activity, tetramisole HCl also exhibits immunomodulatory effects. It can stimulate the immune system, promoting the production of certain white blood cells and enhancing the animal's immune response. This immunomodulatory action may contribute to the overall therapeutic effect of tetramisole HCl in treating parasitic infections.

 

Tetramisole powder mf

 

Certificate of Analysis

ANALYSIS

SPECIFICATION

RESULT

Assay

98%

99.48%

Appearance

White Crystalline Powder

Complies

Identification

Specific optical rotation

Complies

 

Gives reaction of chlorides

Complies

PH

3.0-4.5

4.1

Residue on ignition

≤0.1%

0.06%

Loss on drying

≤0.5%

0.27%

Heavy metals

≤15ppm

﹤3ppm

Hg

Negative

Complies

As

≤2.5ppm

Complies

Pesticide residue

Negative

Complies

Total Plate Count

≤1000cfu/g

Complies

Total Yeast&Mold

≤100cfu/g

Complies

E.Coli

Negative

Complies

Salmonella

Negative

Complies

Staphylococcin

Negative

Complies

 

Where To Buy Tetramisole

Xi'an Sonwu Biotech Co. ltd. has rich experience in global trade and health industry. Insist on faith-based and quality first is our company’s principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce cost to the maximum extent, then our customers can get cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. ltd. when you need it.

 

Xi'an Sonwu completely makes sure product’s quality, so sample can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum of Quantity

Powder

500g

1kg

 

Customers’ Good Comment

comment

 

What Is Tetramisole Used For

Tetramisole, or more specifically tetramisole hydrochloride (HCl), is a medication with several uses in both human and veterinary medicine. It has properties that make it valuable in various applications.

 

1. Veterinary Use:

Tetramisole is primarily used in veterinary medicine as an anthelmintic, which means it is used to treat parasitic infestations in animals. It is effective against a wide range of parasites, including roundworms, hookworms, and lungworms. Tetramisole works by paralyzing and killing the parasites, allowing the animal's immune system or subsequent medications to eliminate them. For example, it can be used to deworm livestock such as sheep, cattle, horses, and pigs.

 

2. Immunomodulatory Effects:

Tetramisole has been found to have immunomodulatory properties. It can stimulate the immune system by enhancing the production and function of certain white blood cells, particularly lymphocytes, leading to a modulation of the immune response. This effect has been studied in various conditions, such as autoimmune disorders and certain types of cancers. However, further research is necessary to fully understand and utilize its immunomodulatory potential.

Tetramisole powder animals

 

What Is The Mechanism Of Action Of Tetramisole Hydrochloride

The mechanism of action of tetramisole hydrochloride (HCl) involves its effects on the nervous system and acetylcholinesterase enzyme activity. Tetramisole HCl is primarily used as an anthelmintic to treat parasitic infections. Let's explore its mechanism of action in more detail:

 

1. Inhibition of Acetylcholinesterase:

Tetramisole HCl acts by inhibiting the activity of the enzyme acetylcholinesterase (AChE). Acetylcholinesterase normally breaks down the neurotransmitter acetylcholine in the nervous system, terminating its signaling. By inhibiting AChE, tetramisole HCl prolongs the action of acetylcholine in the synapses, leading to excessive stimulation of the parasites' nervous system.

 

Tetramisole powder ache

 

2. Paralysis of Parasites:

The prolonged accumulation of acetylcholine in the synaptic cleft causes continuous stimulation of the parasites' cholinergic receptors. This overstimulation ultimately leads to paralysis of the parasites. Tetramisole HCl primarily affects the cholinergic receptors in the neuromuscular junctions of the parasites by preventing the degradation of acetylcholine.

 

3. Spastic Paralysis:

Tetramisole HCl induces a specific type of paralysis known as spastic paralysis in susceptible parasites. Spastic paralysis is characterized by sustained muscle contractions and increased muscle tone due to unopposed cholinergic stimulation. The paralyzed parasites are unable to maintain their grip on the host's tissues, facilitating their elimination from the body.

 

4. Immobilization and Death:

As a result of tetramisole's action on the nervous system, the parasites lose their ability to move, feed, or reproduce. They become immobilized, making it easier for the immune system or subsequent treatments to eliminate them. Eventually, without the necessary metabolic functions, the parasites die.

 

It is worth noting that tetramisole HCl has a relatively selective effect on parasites, as it primarily targets their cholinergic receptors and leaves the host's nervous system largely unaffected. This selectivity is due to differences in the structure and function of the acetylcholine receptors between parasites and mammals.

 

Apart from its activity on the parasites' nervous system, tetramisole HCl has also been found to have immunomodulatory effects. It can stimulate the immune system by enhancing the production and function of certain white blood cells, such as lymphocytes.

 

Tetramisole powder mechainism

 

What Are The Side Effects Of Tetramisole

Tetramisole powder is widely used in veterinary medicine as an anthelmintic to treat parasitic infections in animals. While it is generally safe and effective when used appropriately, there are potential side effects that can occur. Please note that the occurrence and severity of side effects may vary among different species and individuals. Here are some possible side effects associated with veterinary tetramisole:

 

1. Gastrointestinal Effects:

Tetramisole HCl can occasionally cause gastrointestinal disturbances in animals. These effects may include vomiting, diarrhea, or reduced appetite. Such symptoms are usually mild and self-limiting.

 

2. Neurological Effects:

In rare cases, tetramisole HCl may cause neurological side effects in animals. This can include tremors, ataxia (loss of coordination), or seizures. If these symptoms occur, immediate veterinary attention is necessary.

 

3. Hypersensitivity Reactions:

Some animals may exhibit hypersensitivity reactions to tetramisole HCl. This can manifest as skin rashes, itching, swelling, or difficulty breathing. Allergic reactions require immediate veterinary intervention.

 

4. Hematological Effects:

Tetramisole HCl has been associated with occasional hematological changes in animals. This may include a decrease in white blood cells (leukopenia) or platelets (thrombocytopenia). Regular blood monitoring may be necessary during treatment.

 

5. Respiratory Effects:

Rarely, tetramisole HCl can lead to respiratory side effects in animals. This may include coughing, wheezing, or difficulty breathing. If respiratory symptoms occur, veterinary consultation is advised.

 

6. Cardiovascular Effects:

In some cases, tetramisole HCl may affect the cardiovascular system of animals. This can include changes in heart rate or blood pressure. Monitoring by a veterinarian may be necessary, particularly in animals with pre-existing heart conditions.

 

7. Hypersalivation and Drooling:

Some animals may experience excessive salivation or drooling after receiving tetramisole HCl treatment. This is usually temporary and resolves on its own.

 

8. Other Potential Side Effects:

Other less common side effects that have been reported include lethargy, weakness, fever, or changes in liver or kidney function. Monitoring for any unusual symptoms is important.

 

It is important to follow the dosage instructions provided by a veterinarian and to provide accurate bodyweight information when administering tetramisole HCl to animals. Additionally, it is important to be aware of drug interactions with other medications your pet may be taking and to inform the veterinarian about any concurrent treatments.

 

What Is Another Name For Tetramisole

Another name for veterinary tetramisole is levamisole. Levamisole is the active ingredient in tetramisole hydrochloride, which is commonly used in veterinary medicine as an anthelmintic agent to treat parasitic infections in various animal species.

 

Levamisole works by interfering with the neuromuscular function of parasites, ultimately leading to their paralysis and expulsion from the animal's body. It is effective against a wide range of internal parasites, including roundworms and hookworms, making it a valuable tool in veterinary practice.

 

In addition to its anthelmintic properties, levamisole has also been found to possess immunomodulatory effects. It can enhance the immune response in animals, making it useful in certain conditions where immune function needs to be boosted, such as in cases of immunodeficiency or certain types of cancers.

 

The use of levamisole is well-established in veterinary medicine, and it is available in various formulations, including oral preparations, injectables, and topical formulations. The specific formulation and dosage will depend on the target parasite, the animal species, and the intended route of administration.

 

Factory Environment

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

factory a

factory b

 

Cetifications

certificates

 

Packaging

packaging

 

Logistics Record

logistics

 

In addition to guaranteeing the product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi’an Sonwu supply all kinds of couriers according to different needs.

courier

Company's Profile

Xi’an Sonwu Biotech Co . Itd is a professional Chinese manufacturer and products supplier. It was founded in 2012, and located in Hi-Tech industrial Zone Xi’an city, Shannxi province, China. It pays all attention on development, research and production of food additives, plant extract , APl and other ingredients of health care products. Our company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, Plant Extract. We sincerely believe that the premise of a great cooperation is best services and good quality. So, welcome your inquiry.

 

If you want to know tetramisole powder price, feel free to contact Xi'an Sonwu.

E-mail: sales@sonwu.com

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