Lidocaine Powder

What Is Lidocaine?

Lidocaine powder is a widely used anesthetic in the market. Lidocaine, also known as lignocaine, is an aminoamide local anesthetic commonly used for local and topical anesthesia. When used for local anesthesia, lidocaine usually starts to work within a few minutes and lasts for half an hour to three hours. Not only that, but it also has antiarrhythmic and analgesic effects and can be used as an aid in endotracheal intubation. It is usually mixed with a small amount of epinephrine (epinephrine) to prolong its local development and reduce bleeding.

Lidocaine was discovered in 1946 and marketed in 1948. It is an essential medicine on the World Health Organization's list and is available as a generic medicine. As of 2020, it has more than 700,000 prescriptions filled in the United States. This situation has caused it to be widely circulated in the market. As a professional manufacturer of lidocaine, Xi'an Sonwu is favored by many customers for its high quality and high service reputation. If you want to buy products, don't hesitate to get in touch with Xi'an Sonwu to make a purchase.

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Where to Buy Lidocaine？

Xi'an Sonwu Biotech Co. ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum so our customers can get a cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. ltd. when buying lidocaine.

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Application

1. It can be used as a local anesthetic.

Lidocaine is used as a local anesthetic because of its rapid onset and moderate duration of action. Therefore, it is suitable for infiltration, nerve blocks, and topical anesthesia. Lidocaine is one of the most widely used local anesthetics in dentistry. It can be administered in several ways, most commonly by nerve block or infiltration, depending on the treatment and mouth area. For topical anesthesia, several preparations are available for endoscopy, pre-intubation, etc. Lidocaine drops may be used for short-term eye surgery. Topical lidocaine can be used for neuropathic pain and skin graft donor site pain.

2. It can be used to treat cardiac arrhythmias.

Lidocaine is also an essential class 1b antiarrhythmic drug. If amiodarone is not available or contraindicated, it may be used to treat ventricular arrhythmias. Lidocaine should be administered for this indication after initiation of defibrillation, CPR, and vasopressors.

3. It acts as an antitussive.

Lidocaine is helpful when inhaled as a cough suppressant. Because what it does is reduce the cough reflex around it. It is undoubtedly a safe and comfortable measure for patients who must be intubated because it reduces the incidence of coughing and any possible damage to the trachea after the anesthesia has ended.

Lidocaine's Mechanism of Action

Lidocaine usually starts working within four minutes and lasts from half an hour to three hours. Approximately 95% of lidocaine is metabolized in the liver primarily by CYP3A4 to the pharmacologically active metabolite monoethyl glycine xylidine (MEGX), which is then metabolized to the inactive glycinexylidine. This process alters signaling in neurons by prolonging the inactivation of fast voltage-gated Na+ ion channels in the neuronal membrane responsible for the propagation of action potentials. When sufficiently blocked, voltage-gated sodium channels will not open, and action potentials will not be generated. The same principle applies to how the drug works in the heart.

What Are the Classifications of Drugs?

Lidocaine powder, as a veterinary-grade drug, can regulate the functions of livestock and poultry organisms and prevent and treat livestock and poultry diseases. It belongs to the class of central nervous system drugs. These drugs act on the central nervous system's brain and spinal cord; some are inhibitory, and some are excitatory. It can be divided into the following kinds.

①General anesthetics.

These drugs can inhibit the central nervous system of animals, suspend some functions, lose consciousness and sensation, and still maintain the part of the life center of the medulla oblongata. Both halothane and methoxyflurane belong to this class of drugs.

②Local anesthetics.

The function of this type of drug is to block the conduction impulse of nerve endings or nerve trunks so that the parts innervated by the nerves temporarily lose the pain response. Commonly used are procaine, tetracaine, lidocaine, and benzocaine. In clinical application, drugs such as tetracaine and lidocaine, which have solid mucosal penetration, are suitable for topical and epidural anesthesia. Less toxic ones, such as procaine, are suitable for infiltration and conduction anesthesia. Benzocaine, which has weak penetrating power, low toxicity, insoluble in water, and has a long-lasting effect, is only used as an ointment or spraying agent for wounds and burns.

③ sedatives.

These drugs have a mild depressant effect on the central nervous system and can calm animals. It is often used for medical treatment, high temperatures, or transportation. Large doses of the drug can be used as anticonvulsants.

④ Analgesics.

These drugs work to relieve or reduce pain. The synthetic ones include pethidine, fentanyl, analgesic, etc., commonly used in administering medium and small animals before anesthesia and acute colic in horses.

⑤ antipyretic analgesics, antirheumatic drugs.

These drugs can be both antipyretic and analgesic and have anti-inflammatory and anti-rheumatic effects. Its antipyretic mechanism inhibits the hypothalamus's anterior neurons so that it will not synthesize and release pyrogenic substances due to pyrogen stimulation, restoring the reactivity of thermosensitive neurons and exerting the cooling effect to normalize body temperature.

⑥ CNS stimulants.

These drugs have the function of increasing the activity of the central nervous system. Among them, sodium benzoate caffeine directly affects the medullary center and the heart, which can be used for heart weakness caused by respiratory and circulatory failure.

Lidocaine Dosing Information for Dogs and Cats

Never prescribe medication without first consulting your veterinarian.

For arrhythmias in dogs, an initial dose of 1mg to 2 mg per pound (2mg/kg to 4 mg/kg) is administered, followed by 10micrograms to 40 micrograms per pound (20mg/kg to 80 mg/kg) per minute over time. The dose for cats is usually 1/4 that for dogs and must be given very slowly. After a while, the animals were slowly discontinued from lidocaine use. An ECG helps determine if the arrhythmia has been corrected or if more lidocaine or other antiarrhythmic drugs need to be given.

All dosages used should be under the advice of a physician. Please do not do it yourself.

Is Veterinary Lidocaine the Same as Human?

Veterinarians pre-medicate, induce and maintain anesthesia in animals with many of the same drugs used for human anesthesia. However, the species-specific effects of the lidocaine used differed from those in humans.

Factory Environment

1. Xi'an Sonwu Biotech Co., Ltd has its factory, so it has adequate stock. Also, Xi'an Sonwu has a clean and tidy producing department with advanced equipment. With the lead of Xi'an Sonwu, researchers are constantly developing new products to meet customers' needs.

2. Xi'an Sonwu Biotech Co., Ltd has advanced test equipment and professional testers, which all show that Xi'an Sonwu aims to supply accurate and effective data and good service.

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The Latest Logistics Records

Besides guaranteeing the product's quality, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supply all kinds of courier according to different need.

Why Choose Us?

1. OEM Service

2. Support sample testing.

3. Each batch of products is tested to ensure quality.

4. Product packaging can be customized according to customer requirements.

5. Inquiry will be replied to within 24 hours to provide customers customized products and services.

If you need to buy lidocaine powder, you can contact Xi'an Sonwu directly.

E-mail: sales@sonwu.com 

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