Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of carbasalate calcium powder in China. We warmly welcome yuo to wholesale bulk carbasalate calcium powder for sale here from our factory. Quality products and reasonable price are available.
What Is Carbasalate Calcium
Carbasalate calcium powder is a medication that belongs to the class of drugs called salicylates that is used for its anti-inflammatory, analgesic (pain-relieving), antipyretic and cardiovascular protection properties. It is derived from aspirin (acetylsalicylic acid) and is commonly used as an alternative to aspirin due to its lower gastrointestinal side effects. Carbasalate calcium powder works by inhibiting the production of prostaglandins, which are chemical messengers involved in pain, inflammation, and fever.
The primary mechanism of action of carbasalate calcium is the inhibition of the cyclooxygenase (COX) enzyme, which is responsible for the synthesis of prostaglandins. By inhibiting COX, carbasalate calcium decreases the production of prostaglandins, which in turn reduces pain, inflammation, and fever. Additionally, its antiplatelet effects help to prevent blood clot formation.
In veterinary medicine, carbasalate calcium powder is commonly used for horses to manage pain and inflammation associated with musculoskeletal conditions like arthritis. It is administered orally and can be mixed with a carrier substance to facilitate easy ingestion by the animal.
The purity of our company's carbasalate calcium capsule supplement can reach 99%. Also, our prices are very competitive compared to other companies. If you want to know more, don't hesitate to get in touch with Xi'an Sonwu Biotech Co. Ltd.
Carbasalate Calcium Buy
Xi'an Sonwu has rich experience in the global trade and health industry. Reputation-based quality first is the principle of Xi' an Sonwu Company. Xi'an Sonwu strictly controls product quality, so the selection of materials starts with raw materials. Also, we handle every detail and minimize costs so our clients can get the most cost-effective products. Based on these, customers have given high praise to our products. If you need carbasalate calcium capsule supplement, find Xi’an Sonwu Biotech Co. Ltd.
We ultimately make sure of the product’s quality so that samples can be supplied. Here is the quantity.
|
Form |
Sample Amount |
The Minimum of Quantity |
|
Powder |
10g |
10g |
|
Bulk Capsules |
200 capsules |
200 capsules |
|
Bottled Capsules |
5 bottles |
5 bottles |
Customers' Good Comment
OEM Service
Xi'an Sonwu not only can supply high-quality carbasalate calcium powder, but also supply carbasalate calcium capsules.
So any customers could customize the capsules they want. And items below can be supplied.
Customized capsules shells (size, color, material)
Customized bottles(size, color, material, style)
Customized packaging(vacuum foil packaging, box, drum)
Customized label(paint film, matte film, optical mask)
What Is the Drug Carbasalate Calcium Used for
1. Pain Management:
Carbaspirin calcium is commonly used as an analgesic to relieve mild to moderate pain. It can alleviate a wide range of pain, including headaches, dental pain, menstrual pain, and musculoskeletal pain. Its analgesic properties are attributed to its ability to inhibit prostaglandin synthesis and reduce inflammation, ultimately reducing pain perception.
2. Anti-inflammatory Effects:
Carbaspirin calcium possesses potent anti-inflammatory properties due to its inhibition of the cyclooxygenase (COX) enzyme, thereby reducing the production of inflammatory prostaglandins. It is particularly useful in the management of conditions characterized by inflammation, such as rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases.
3. Fever Reduction:
Carbaspirin calcium has antipyretic properties, making it effective in reducing fever associated with various conditions, including infections and inflammatory processes.
By inhibiting the synthesis of prostaglandins in the hypothalamus, it helps normalize body temperature during fever episodes.
4. Cardiovascular Protection:
Carbaspirin calcium, like aspirin, possesses antiplatelet effects. It inhibits the aggregation of platelets, reducing the risk of blood clot formation.
This property is utilized in cardiovascular conditions, such as preventing heart attacks, strokes, and other thrombotic events.
It is often prescribed as a preventive measure for individuals with a history of cardiovascular disease or those at high risk for developing it.
5. Thromboprophylaxis:
Carbaspirin calcium is used as a prophylactic medication to prevent blood clot formation in various clinical settings.
It can be prescribed to individuals undergoing major surgeries, such as hip or knee replacement, to reduce the risk of postoperative deep vein thrombosis (DVT) or pulmonary embolism (PE).
It may also be employed in certain medical conditions, such as atrial fibrillation, where there is an increased risk of clot formation in the heart.
6. Preventive Measure for Certain Cancers:
Some studies suggest that long-term use of carbaspirin calcium or aspirin may have a protective effect against certain types of cancers, particularly colorectal cancer.
However, the use of carbaspirin calcium as a cancer preventive measure requires careful consideration and should only be recommended by healthcare professionals based on an individual's risk profile.
Mechanism of Action of Carbasalate Calcium
The mechanism of action of carbasalate calcium involves its ability to inhibit the cyclooxygenase (COX) enzyme, thus reducing the synthesis of prostaglandins. Prostaglandins are lipid mediators that play a crucial role in mediating inflammation, pain perception, and fever response in the body. By inhibiting the production of prostaglandins, carbasalate calcium exerts its anti-inflammatory, analgesic, and antipyretic effects.
Introduction to COX Enzyme:
The cyclooxygenase (COX) enzyme is responsible for catalyzing the conversion of arachidonic acid into prostaglandins.
There are two isoforms of COX: COX-1 and COX-2. COX-1 is constitutively expressed and involved in physiological functions, while COX-2 is induced during inflammation and plays a role in pathological processes.
Inhibition of COX Enzyme by Carbasalate Calcium:
Carbasalate calcium is structurally similar to acetylsalicylic acid, also known as aspirin.
After administration, carbasalate calcium is hydrolyzed in the body to release acetylsalicylate ions, which are responsible for its pharmacological activity.
Acetylsalicylate ions irreversibly bind to the active site of COX enzymes, inhibiting their activity.
Impact on Prostaglandin Synthesis:
Inhibition of COX enzymes by carbasalate calcium leads to a decrease in the conversion of arachidonic acid to prostaglandin H2, the precursor of various prostaglandins.
Prostaglandins play a vital role in mediating inflammation, pain, and fever by sensitizing pain receptors, increasing blood flow, and promoting the immune response.
By reducing prostaglandin synthesis, carbasalate calcium suppresses these pro-inflammatory mediators and their associated effects.
Anti-inflammatory Effects:
Inhibition of prostaglandin synthesis by carbasalate calcium leads to a decrease in inflammation.
Prostaglandins are responsible for vasodilation and increased vascular permeability, which are hallmarks of inflammation.
By limiting the production of prostaglandins, carbasalate calcium helps to reduce inflammation, swelling, and erythema associated with various inflammatory conditions.
Analgesic Effects:
Prostaglandins sensitize pain receptors, thereby increasing the perception of pain.
Carbasalate calcium's inhibition of prostaglandin synthesis helps to alleviate pain by reducing the sensitization of pain receptors.
It is particularly effective in reducing pain associated with inflammation, such as in arthritis or musculoskeletal injuries.
Antipyretic Effects:
Prostaglandins have a pyrogenic effect on the hypothalamus, which leads to an increase in body temperature during fever.
Carbasalate calcium's ability to inhibit prostaglandin synthesis helps to lower fever by preventing the pyrogenic effect on the hypothalamus.
It is commonly used to reduce fever in conditions such as influenza or other febrile illnesses.
Selectivity and COX-1/COX-2 Ratio:
Carbasalate calcium exhibits a moderate selectivity for COX-1 over COX-2.
COX-1 inhibition can lead to adverse effects on gastric mucosa and platelet aggregation, while COX-2 inhibition primarily targets inflammation.
The selectivity profile of carbasalate calcium contributes to its analgesic and anti-inflammatory effects while minimizing certain gastrointestinal side effects associated with COX-1 inhibition.
Additional Effects and Considerations:
Carbasalate calcium also inhibits the activation of blood platelets, contributing to its antiplatelet effects.
The irreversible COX inhibition by carbasalate calcium lasts for the lifespan of the platelets, which is about 7-10 days.
This platelet-inhibitory effect is the basis for its use in the prevention of certain cardiovascular conditions, such as stroke and heart attack.
Carbasalate Calcium Side Effects
1. Gastrointestinal Effects:
One of the most well-known side effects of carbasalate calcium is gastrointestinal irritation, which may manifest as stomach pain, indigestion, or heartburn.
Prolonged use or high doses of carbasalate calcium can lead to erosions or ulcers in the stomach or intestines, which can result in gastrointestinal bleeding.
2. Allergic Reactions:
Some individuals may experience allergic reactions to carbasalate calcium, including rash, itching, hives, or swelling of the face, lips, tongue, or throat.
Severe allergic reactions such as anaphylaxis, though rare, can occur and are considered medical emergencies.
3. Respiratory Effects:
Carbasalate calcium, like other NSAIDs (nonsteroidal anti-inflammatory drugs), has the potential to cause asthma exacerbations or induce bronchospasms in individuals with a history of asthma or other respiratory conditions.
It is important for individuals with respiratory conditions to consult their healthcare provider before using carbasalate calcium.
4. Renal Effects:
Prolonged use or high doses of carbasalate calcium may impact kidney function and lead to fluid retention, edema, or worsening of pre-existing kidney conditions.
Individuals with impaired renal function or a history of kidney disease should use caution and consult their healthcare provider before using carbasalate calcium.
5. Bleeding Risk:
Carbasalate calcium's antiplatelet effects increase the risk of bleeding, particularly in individuals undergoing surgical procedures or those with bleeding disorders.
It is important to inform healthcare professionals about carbasalate calcium use prior to any surgical procedures, including dental procedures.
6. Dizziness and Tinnitus:
Some individuals may experience dizziness or ringing in the ears (tinnitus) while taking carbasalate calcium.
These symptoms are usually temporary and resolve upon discontinuation of the medication. However, if they persist or worsen, medical advice should be sought.
7. Interactions with Other Medications:
Carbasalate calcium may interact with other medications, potentially increasing the risk of side effects.
It is important to inform healthcare professionals about all medications being taken, including over-the-counter medications, herbal supplements, and vitamins, to ensure safe and appropriate use.
8. Other Considerations:
Carbasalate calcium should be used with caution in individuals with certain medical conditions such as liver disease, clotting disorders, or individuals who consume alcohol regularly.
Pregnant women, particularly in the third trimester, should avoid using carbasalate calcium due to the risk of adverse effects on the fetus and complications during labor.
Factory
Xi'an Sonwu is located in a place with a beautiful natural environment, covering an area of 10,000 square meters. The factory has advanced production equipment, and the technical team is well-equipped, clean, and tidy, with sufficient stock. Under the leadership of the company, researchers insist on developing new products. The following is the testing environment of our laboratory, advanced testing equipment, and professional testers, with a strict attitude to providing valuable data for our products and providing our customers with a quality experience.
Certificate
Packaging
Recent Logistics Record
In addition to guaranteeing product quality, the other most vital thing is clients can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
FAQ
1. How to inquiry?
You can contact us by email, telephone number, or social media.
2. How to guarantee the quality of products?
Each batch needs to be tested so we can supply COA for customers. Additionally, our products pass the test: HPLC, UV, GC, TLC, etc. And we also cooperate with third parties, like, SGS.
3. How to pack and store the product?
Pack: Vacuum sealed foil packaging & Sealed export grade drum or pack according to customers' need
Storage: For a short time, you can keep it in a dry and cool place and make it avoid sunlight.
If you are interested in our company's carbasalate calcium powder, please contact Xi'an Sonwu Biotech Co. Ltd.
Email: sales@sonwu.com
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