Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of synephrine hcl powder in China. We warmly welcome yuo to wholesale bulk synephrine hcl powder for sale here from our factory. Quality products and reasonable price are available.
What Is Synephrine HCl
Synephrine Hcl powder alias 1-(4-hydroxyphenyl)-2-(methylamino)ethanol. Synephrine belongs to the ephedrine class of alkaloids, and its molecular structure contains phenolic hydroxyl and amino groups. Therefore, synephrine has amphoteric properties and can combine with acids and bases to form salts. Free synephrine is easily soluble in organic solvents but insoluble in water; its acidic and basic salts are readily soluble in water but insoluble in organic solvents.
Synephrine hydrochloride has the effect of constricting blood vessels and raising blood pressure. Synephrine has a strong influence on dilating the trachea and bronchi. Intravenous injection of anesthetized cats can completely resist the bronchoconstriction caused by histamine, and it has the same effect on the isolated trachea of guinea pigs. Synephrine hydrochloride is clinically used to treat bronchial asthma, hypotension, collapse and shock, and orthostatic hypotension during surgery and anesthesia. Synephrine is a natural stimulant in the 21st century, without any side effects and positive reactions. It is widely used in healthcare industries such as medicine, food, and beverages. With the prohibition of chemically synthesized drugs, the demand and value of synephrine will double. L-synephrine exists in plants such as dried young fruits of lime and citrus, Aurantium, and green bark; the content is only 0.28-2.53%. Xi'an Sonwnu can provide high-purity synephrine hcl supplements, and if you want to buy them, you can contact Xi'an Sonwnu without hesitation.
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Where to Buy Synephrine Hcl
Xi'an Sonwu Biotech Co. ltd, the products produced are strictly controlled in quality from the beginning of the raw material powder. In processing product production, we handle every detail well and enable our customers to get cost-effective products. Many customers have given good feedback to our products after receiving the goods.
To ensure the quality of the products, we can provide samples for testing. Here is the quantity.
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10g |
100g |
Customers’s Good Comment
What Are The Benefits Of Synephrine HCl
Synephrine Hcl powder can be used as a pressor drug for shock, heart failure, bronchial asthma, base blood pressure during surgery and anesthesia, collapse and shock, body and position hypotension α-adrenoceptor agonist, Vasoconstrictor, etc.
1. The effect on cardiovascular
The intravenous injection of citrus Aurantium, citrus Aurantium decoction, citrus Aurantium extract, citrus Aurantium injection, and its active ingredient synephrine hydrochloride can significantly enhance various indicators of myocardial contractility and pumping function in anesthetized dogs and has the effect of strengthening the heart. , Constrict blood vessels, increase total peripheral resistance, and increase left ventricular and arterial blood pressure. Modern studies have also confirmed that Citrus aurantium can increase the tension of the rabbit aorta in a concentration-dependent manner and make the aortic smooth muscle contract.
2. Effects on weight loss
Synephrine hydrochloride is used as a weight loss accelerator, and its mechanism of action is to stimulate the β-3 adrenergic receptor to cause lipid decomposition and subsequent thermogenesis. Most dietary supplements containing synephrine HCl contain various other ingredients, mainly caffeine, salicylic acid, and ephedrine. Combining those mentioned above multiple chemical components can improve the weight-loss effect of synephrine hydrochloride. Taking rats as the research object, repeated oral administration of commercially available lime hydroalcoholic extract with standardized synephrine hydrochloride was used to evaluate food intake and cardiovascular function. It was found that lime extract could reduce food intake and weight gain, and the animal's electrocardiogram was abnormal in the experimental group.
3. Effects on bronchi
By anesthetizing cats, intravenous injection of synephrine hydrochloride completely antagonized the bronchoconstriction induced by histamine; it also had the same effect on isolated organs of guinea pigs.
4. Effects on depression
Some scholars have studied the antidepressant effect of p-synephrine hydrochloride by establishing the mouse tail suspension test and the mouse forced swimming test depression model, taking the immobilized disappointment time as the index, and administering a dose of 1 to 10 mg/kg ( 0.5m L/25g body weight), significantly reducing its immobility time. Psychedelic drugs can reduce immobility time but stimulate autonomic activity. P-synephrine hydrochloride was administered orally at 0.3-10 mg/kg. It was found that no significant changes occurred in the autonomic activity of mice in the open-field experiment, excluding p-synephrine hydrochloride. The psychostimulant effects of Flynn. P-Synephrine hydrochloride has a pronounced antidepressant impact on the animal depression model of behavioral despair, which can oppress its disappointment behavior and reduce despair behavior (immobilization time), which may be related to stimulation of α-1 adrenoceptor. Possibly therapeutic for its antidepressant effect in hypotensive patients.
5. Effects on blood pressure
In pharmacology, synephrine hydrochloride is used as a decongestant to treat hypotension in oral form. Taking ten healthy adults as objects, the effect of dietary supplements containing lime extract on hemodynamics was studied, and it was proved that some nutritional supplements could improve blood pressure and cardiovascular stimulation in healthy, normotensive subjects, possibly It is produced synergistically with caffeine and other stimulants in a multi-ingredient formula. Animal studies have shown that synephrine hydrochloride and lime extract raise blood pressure. Taking lime extract (6% synephrine hydrochloride) and 8 ounces of fruit juice (containing about 13-14mg synephrine hydrochloride) for six consecutive weeks found that the blood pressure of the subjects did not have any significant effect, evaluating synephrine hydrochloride Effects on blood pressure may require more extended study periods. The literature also reported that Singer has a powerful boosting effect, strengthens myocardial contractility, slows the heart rate, and increases cardiac output, coronary flow, and renal blood flow.
6. Effects on diabetes
The effect of the citrus extract on the liver antioxidant defense function of experimental diabetic mice. Diabetic mice were treated with high, medium, and low doses of citrus extract, and the antioxidant capacity of the liver and morphology were observed. Learn to change. Compared with the diabetes model group, the citrus extract treatment group had significantly lower blood sugar levels (p<0.05), significantly increased glutathione content (p<0.05), glutathione peroxidase activity, malondialdehyde, and Nitrogen oxide content was significantly reduced (p < 0.01), outpaced by an increase in oxide dismutase activity. Under the light microscope, the injury of liver tissue cells in the treatment group of Citrus aurantium extract was lower than that of the diabetes group, indicating that the section of Citrus aurantium can enhance the antioxidant capacity of the liver and reduce the damage to liver cells.
What Are The Side Effects Of Synephrine
Due to the adrenaline-stimulating effects of synephrine hydrochloride, Aurantium extract should be avoided in patients with severe hypertension, tachyarrhythmias, narrow-angle glaucoma, and recipients of monoamine oxidase inhibitors. Synephrine hydrochloride can cause periodic migraines and primary headaches. Literature research shows that dietary supplements containing synephrine hydrochloride contain other drugs, such as methylxanthine, ephedrine, and taurine. Methylxanthine toxicity manifests as tremors, tachycardia, and seizures. Ephedrine, which stimulates the central nervous system, can cause side effects such as heart failure and stroke. The presence of such substances will increase the product's side effects and cause health threats. But in most dietary supplements containing lime extract, p-synephrine hydrochloride is present with other herbal ingredients, including caffeine. Therefore, it is difficult to assess its side effects alone. Taking albino mice as the research object, the acute toxicity of lime extract and p-synephrine hydrochloride was evaluated by spontaneous movement test, body temperature effect, etc. Feeding dose of 1000-5000mg/kg lime extract (2.5% p-synephrine hydrochloride), after 15 minutes, the spontaneous locomotor activity decreased significantly, and p-synephrine hydrochloride (150-2000mg/kg) 15 minutes, hair erection appeared, panting, salivation and other apparent symptoms decreased spontaneous motor activity, the above symptoms lasted 3 to 4h, are reversible. An autopsy of the isolated organs revealed no abnormalities. The observed toxic effects are related to the corresponding adrenergic stimulation; p-synephrine hydrochloride acts not only on β3-adrenergic receptors but also on β2-adrenergic receptors and α1-adrenergic receptors.
Factory Environment
1. Xi'an Sonwu Biotech Co., Ltd has a factory with sufficient stock. In addition, the production department of Xi'an Matsuya is very clean and tidy. Using advanced production equipment, researchers continue developing new products to meet customers' needs.
2. Xi'an Sonwu Biotech Co., Ltd has advanced testing equipment and professional testing personnel, which has laid a solid foundation for providing customers with accurate and practical data.
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Except guarantee the product’s, the other most important thing is customers could receive the goods smoothly. So, Xi’an Sonwu supplies all kinds of courier according to different need.
FAQ
How to pack and store Synephrine Hcl powder?
Packaging: export grade sealed drum, vacuum sealed aluminum foil packaging, can also be packed according to customer needs.
Storage: please store in a cool and dry place to avoid bright light and high temperature.
If you want to buy Synephrine Hcl, feel free to contact Xi'an Sonwu.
E-mail: sales@sonwu.com
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