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Tianeptine Sulfate Powder

Tianeptine Sulfate Powder

Appearance: White Crystal Powder
Specification: NLT99%
CAS: 1224690-84-9
Molecular Formula: C21H27ClN2O8S2
Molecular Weight: 233.27
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package, Capsules)

Product Introduction

Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of tianeptine sulfate powder in China. We warmly welcome yuo to wholesale bulk tianeptine sulfate powder for sale here from our factory. Quality products and reasonable price are available.

 

What Is Tianeptine Sulfate

Tianeptine sulfate powder is a well known product treating depression and anxiety in some European, Asian, and Latin American countries. It is classified as an atypical antidepressant and is mainly used to treat severe depression. It can also be used for the treatment of asthma, anxiety disorders, and irritable bowel syndrome. This drug has an anti-anxiety effect and is relatively lacking in sedation, anticholinergic, and cardiovascular side effects. The French Medical Research Association discovered and patented the substance in the 1960s.

Xi'an Sonwu Biotech Co. Ltd. mains to do tianeptine wholesale business, and promises to supply high purity tianeptine sufate bulk powder. The advanced equipment makes sure the clients get the most cost-effective product. If you want to know more , do not hesitate to contact Xi'an Sonwu Biotech Co. Ltd.

Tianeptine Sulfate mf


Certificate of Analysis

ANALYSIS

SPECIFICATION

RUSULT

Appearance

White or almost white crystalline powder

Conforms

Solubility

Soluble in DMF, insoluble in the water and dichloromethane

Conforms

Identification

( 1)By IR, To match with working standard (2 ) It gives reaction of sulfate

Conforms

Impurities A

≤0. 1%

Not Detected

Related Compounds

Any impurity ≤0. 1%

0.07%

Total Impuritie

≤0.4%

0. 14%

Loss on Drying

≤5%

2.63%

Residue on Ignition

≤0.1%

0.07%

Heavy Mental

≤10ppm

Conforms

Residual Solvents

Should comply to the requirement

Conforms

Assay

99.0%- 101 .0%(On anhydrous basis)

99.99%


Where to Buy Tianeptine Sulfate

Xi'an Sonwu Biotech Co. Ltd. has rich experience in global trade and health industry. Insist on faith-based and quality first is our company’s principle. We strictly control product quality, which means selection starts from raw material. Besides, we handle every detail and reduce cost to the maximum extent, then our customers can get cost-effective product. Based on these, customers have given much good feedback to our products. So look for Xi'an Sonwu Biotech Co. ltd. if you are interested in tianeptine products, we also supply tianeptine sodium, powder, tianeptine free acid and tianeptine ethyl ester.


We completely make sure product’s quality, so sample can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum of Quantity

Powder

5g

10g

Bulk Capsules

200 capsules

200 capsules

Bottled Capsules

5 bottles

5 bottles

Liquid

5 bottles

5 bottles


Customers’s Good Comment

comment


OEM Service

Xi'an Sonwu Biotech Co. Ltd. not only can supply high quality tianeptine sulfate powder, but also supply tianeptine sulfate capsules.

So any customers could customize capsules they want. And items below can be supplied.

1. Customized capsules shells (size, color, material)

2. Customized bottles(size, color, material, style)

3. Customized packaging(vacuum foil packaging, box, drum)

4. Customized label(paint film, matte film, optical mask)

Tianeptine Sulfate


What Is Tianeptine Sulfate Used for

In approved countries, tianeptine is mainly used to treat depression and anxiety disorders, but some doctors may prescribe it to treat other diseases, such as asthma and irritable bowel syndrome. If your doctor prescribes tianeptine, please follow your treatment plan carefully. Do not change the dose or stop the medication without discussing it with your doctor.


1. Depressive symptoms.

Tianeptine is as effective as several traditional antidepressants in patients with severe depression, mood disorders, or adaptation disorders. In addition, prolonged treatment of tianeptine reduced the incidence of recurrence of depression.


In a clinical trial of 18 patients with Parkinson's disease (PD), tianeptine reduced the severity of depression and improved their quality of life.

Tianeptine helps relieve drug-induced seizures and learning and memory disorders in rats. This study suggests that tianeptine may be beneficial to depressed patients with epilepsy.


Due to the relative lack of sedation, anticholinergic and cardiovascular adverse reactions, tianeptine may have additional potential for specific subgroups of patients with depression, such as the elderly and patients with chronic alcoholism.

Tianeptine helps relieve depression in postmenopausal women and may reduce appetite. However, it does not affect body weight for a long time and is not used in obesity treatment.


2. Anxiety, stress, and PTSD symptoms.

In a clinical trial of 164 elderly patients with depression, tianeptine or escitalopram improved anxiety symptoms and subjective and objective neurocognitive function.


In another trial of 20 patients with panic attacks, tianeptine seemed to reduce their response to panic challenges.

In a study of 90 people, tianeptine (at a dose of 37.5mg) was effective in treating patients with post-traumatic stress disorder (PTSD) compared with the control group.


Tianeptine was the most effective in preventing the effects of psychosocial stress in rats with predator-induced post-traumatic stress disorder (PTSD).

In rats, tianeptine increased respiration and prevented a morphine-induced respiratory depression.

In rats given tianeptine, regression learning and memory increased. This suggests that tianeptine can change learning behavior based on exposure therapy.

Tianeptine has memory protection properties because it can block the adverse effects of stress on hippocampal-dependent learning and memory. In rats, tianeptine prevented stress-induced memory errors in two different tasks.

In an experiment in which maternal-deprived rats were subjected to swimming and field trials, tianeptine helped them cope better with stress (reducing inactivity time and increasing swimming time).


In female rats, tianeptine reduced stress + lipopolysaccharide (LPS) effect on BDNF levels more significantly than desipramine and fluoxetine (antidepressants).

Tianeptine, along with similar antidepressants, helped restore biomolecule damage caused by stress in mice.

In stressed rats, tianeptine reversed the decrease of catalase activity induced by saline.

Tianeptine Sulfate benefits


3. Asthma.

During asthma attacks, catecholamines and free serotonin circulate in the blood. Tianeptine reduces free serotonin in the blood by increasing serotonin uptake by platelets and serotonergic brain cells. Free serotonin is absorbed by lung cells and induces bronchoconstriction (through 5-HT (3) and 5-HT (4) postsynaptic receptors).


In a clinical trial of 25000 patients with asthma, tianeptine treatment caused asthma attacks to disappear suddenly.

In another trial of 69 children with asthma, tianeptine reduced free serotonin levels and improved lung function.


4. Irritable bowel syndrome.

Serotonin plays a vital role in the intestinal nervous system, which controls the movement of intestinal secretions and digestive substances. Increased serotonin can lead to increased secretions and exercise, leading to pain, abdominal distension, and diarrhea in patients with irritable bowel syndrome.


Tianeptine can reduce serotonin activity, thereby improving symptoms associated with IBS and non-ulcerative dyspepsia.

In clinical trials of 122 people, tianeptine was effective as the standard drug for treating IBS-D (irritable bowel syndrome with diarrhea) (amitriptyline).

In another trial of 100 patients with IBS-D or IBS-C (constipated irritable bowel syndrome), tianeptine improved symptoms and quality of life in both groups, especially IBS-C.


Tianeptine Sulfate Dose

For people of average weight, the usual dose is 12 milligrams, three times a day, but some increase it to 25 milligrams at a time (three times a day).


Tianeptine Side Effects

The side effects of tianeptine are similar to those of SSRIs. These include nausea, constipation, abdominal pain, headache, dizziness, and changes in dreaming. If you have severe, mild, or persistent adverse reactions after taking tianeptine, consult your doctor.


Elderly patients should take smaller doses of tianeptine, as should patients with renal failure.

Patients with alcoholism or liver insufficiency or patients undergoing dialysis do not need to adjust the dose.


How Does Tianeptine Work

Tianeptine challenges the monoaminergic hypothesis of depression and the widely supported monoaminergic mechanism, which explains the effects of most known antidepressants. Specifically, the drug is thought to continuously alter the rupture of glutamate receptors in hippocampal CA3 junctions and synapses. Current studies have shown that tianeptine has an antidepressant effect by regulating glutamate receptor activity, such as AMPA receptor and NMDA receptor, and affects the release of brain-derived neurotrophic factor (BDNF), thus affecting neuroplasticity. Recent studies support the role of tianeptine in regulating glutaminergic activity in the amygdala, an emotional area of the brain associated with memory.

Tianeptine Sulfate mechanism


Factory Environment

1. Xi'an Sonwu Biotech Co. Ltd. has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu Biotech Co. Ltd. has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

factory a

factory b


Certificates

certificates


Logistics Record

logistics


In addition to guaranteeing the product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu Biotech Co. Ltd. supply all kinds of couriers according to different needs.

courier

Why Choose Xi'an Sonwu Biotech Co. Ltd.

1.Strong Strength

Owning our own producing workshop and OEM factory, and lab.

2. Experienced

Doing export business to all over the world for more than 8 years.

3. Professional team

Having perfect R&, sales and service team.

4. Sincere Service

Having perfect R&,sales and service team.Having been in the industry for many years, the customer praise rate has reached 99%.

5. Customers' review

Having been in the industry for many years, the customer praise rate has reached 99%.


If you want to know tianeptine sulfate powder price, feel free to contact Xi'an Sonwu Biotech Co. Ltd.

E-mail: sales@sonwu.com

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