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BAM 15 Powder

BAM 15 Powder

Appearance: White Powder
Specification: 98%
CAS: 210302-17-3
Molecular Formula: C16H10F2N6O
Molecular Weight: 340.29
Shelf Life: 2 Years Proper Storage
Stock: Adequate Stock
Certificate: ISO,GMP, HACCP SGS
Service: OEM Service(Private Package, Capsules)

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Product Introduction

What Does BAM15 Do

BAM 15 powder (chemical name: 2-[[4-(2,3-dihydroxypropyl)-1,3-dioxolan-2-yl]methyl]thiazolium chloride) is a small molecule compound that belongs to the category of mitochondrial uncouplers. It regulates the energy metabolism of cells by interfering with the proton gradient in mitochondria. The role of uncouplers is to disrupt the proton gradient of the cell's inner membrane, resulting in the inability of protons to flow back through ATP synthase, thereby reducing the production of ATP and causing the energy generated in the metabolic process to be lost in the form of heat. It is through this mechanism that BAM 15 affects the energy production and metabolic processes of cells. The chemical structure of BAM 15 consists of a thiazole ring, a dioxane ring, and a modified alkyl side chain. The thiazole ring in BAM15 contains nitrogen atoms, allowing it to bind to the mitochondrial membrane in cells. Its dioxane ring, with an alcohol-modified side chain, facilitates specific reactions within the cell. This structure enables BAM15 to penetrate the mitochondrial double membrane and exert an uncoupling effect by interacting with the proton gradient of the inner mitochondrial membrane. Mitochondrial uncoupling works by disrupting the proton gradient during oxidative phosphorylation, where protons are allowed to pass through the inner membrane directly, preventing their return via ATP synthase. This inhibition of ATP production leads to energy being converted into heat, increasing cellular energy expenditure. BAM15's potential application in metabolism lies in its ability to regulate energy metabolism, affecting body weight, sugar metabolism, and fatty acid oxidation. As an uncoupler, it could assist in treating metabolic diseases like obesity and diabetes by increasing calorie consumption. By elevating the basal metabolic rate, BAM15 promotes fat oxidation and heat dissipation, supporting weight reduction and improving insulin sensitivity. While research on BAM15 is still in its early stages, its potential as a mitochondrial uncoupler has garnered significant attention. Animal model studies show that BAM15 can boost energy consumption, slow obesity development, and positively impact diabetes, providing a theoretical foundation for its use in treating metabolic disorders.

BAM15 powder has received many good comments and feedback from customs as one of the most popular products. What attracts customers most is the high quality. Xi'an Sonwu has an exceedingly competitive price. If you want to know more about it, contact Xi'an Sonwu Biotech Co., Ltd.

BAM15 chemical formula

 

Certificate Of Analysis

Items

Standards

Results

Appearance

White Powder

Conform

Odor

Characteristic

Conform

Assay

≥98.0%

98.81%

Particle Size

100% pass 80mesh

Conform

Moisture

<5.0%

Conform

Ash Content

<4.0%

Conform

Solvent Residue

Eur.Pharm

Conform

Total Heavy Metals

<10 ppm

Conform

Arsenic

<1.0 ppm

Conform

Lead

<1.0 ppm

Conform

Mercury

<0.5 ppm

Conform

DDT

<0.2ppm

Conform

E. Coli

Negative

Negative

GMO Status

Complies

GMO Free

Irradiation

Complies

Irradiation Free

 

Where Is BAM15 Found

Xi'an Sonwu Biotech Co. Ltd. has rich experience in global trade and the health industry. Its principle is to insist on faith-based and quality-first practices. Xi'an Sonwu strictly controls product quality, meaning selection starts from raw materials. Besides, Xi'an Sonwu handles every detail and reduces costs to the maximum extent so that customers can get cost-effective products. Based on these, customers have given good feedback on the products. So look for Xi'an Sonwu Biotech Co. Ltd. when buying it.

 

Xi'an Sonwu ensures the product's quality so that the samples can be supplied. Here is the quantity.

Form

Sample Amount

The Minimum Of Quantity

Powder

5g

5g

Bulk capsules

1000 capsules

1000 capsules

Bottle capsules

10 bottles

10 bottles

 

Customers' Good Comment

comment

 

OEM Service

Xi'an Sonwu can supply not only high-quality powder but also BAM15 capsules.

So customers can customize the capsules they want. The items below can be supplied.

1. Customized capsules shells (size, color, material)

2. Customized bottles(size, color, material, style)

3. Customized packaging(vacuum foil packaging, box, drum)

4. Customized label(paint film, matte film, optical mask)

OEM BAM15

 

Is BAM15 Safe

BAM 15 powder is a small molecule mitochondrial uncoupler that produces unique physiological effects mainly by regulating intracellular energy metabolism. Its primary function is to interfere with the proton gradient in mitochondria, inhibit the synthesis of ATP, increase energy consumption, and release energy in heat. Usually, mitochondria use the electron transport chain to generate ATP through oxidative phosphorylation. BAM 15 uncouples this process so that protons cannot effectively flow back to the mitochondrial matrix, thereby reducing the generation of ATP. The uncoupling effect of BAM 15 is mainly reflected in the increase of heat production and the improvement of basal metabolic rate. Through uncoupling, BAM 15 prompts cells to convert excess chemical energy into heat energy, thereby increasing energy consumption. This feature gives BAM 15 the potential to regulate body weight and improve metabolic health, especially in treating diseases such as obesity and diabetes, where it may play a positive role. Studies have shown that BAM15 can promote the oxidation of fatty acids, help reduce fat storage, improve insulin sensitivity, and control blood sugar levels. Therefore, it may become a potential drug for improving insulin resistance and slowing obesity. The use of BAM 15 helps to improve the oxidative utilization of fat by cells, thereby promoting fat decomposition and reducing weight. Although BAM 15 has shown positive effects in experimental animals, its potential as a clinical therapeutic drug still needs further verification. Safety and side effects of long-term use require more research, especially the long-term impact on mitochondrial function. Therefore, the clinical application of BAM15 is still in the research stage, and more experimental data is needed to support its effectiveness and safety.

Mitochondria

 

BAM (mitochondrial uncoupler) is a class of small molecule compounds that can destroy the proton gradient of the inner membrane of mitochondria and regulate cellular energy metabolism. Its mechanism of action is mainly achieved by uncoupling the oxidative phosphorylation process of mitochondria. Under normal circumstances, mitochondria generate ATP through oxidative phosphorylation. In the electron transport chain, the flow of electrons pushes protons through the inner membrane of mitochondria to form a transmembrane proton gradient. This proton gradient drives ATP synthase to generate ATP and store the energy the cell requires. BAM destroys this proton gradient, causing protons to be unable to re-enter the mitochondrial matrix through ATP synthase effectively. It increases the penetration of protons by interacting with lipids in the inner membrane of mitochondria, causing protons to leak into the mitochondrial matrix, thereby weakening the oxidative phosphorylation process. Due to the reduced ATP synthesis, cells must consume more energy to maintain basic metabolic processes, increasing energy consumption and heat release. This uncoupling effect causes cells to shift from the traditional ATP production mechanism to a non-ATP-producing energy consumption mode, resulting in increased heat generation. This property gives BAM potential in addressing metabolic diseases by promoting fat oxidation and weight loss. By raising the basal metabolic rate, BAM aids in fatty acid oxidation, enhances insulin sensitivity, and reduces fat storage, making it especially effective for treating obesity and diabetes. Overall, BAM works by uncoupling mitochondrial oxidative phosphorylation, boosting energy consumption and heat production, offering a novel approach for treating metabolic disorders.

Muscle Growth

 

BAM holds great promise for studying and treating metabolic diseases. It supports weight regulation and enhances metabolic function by uncoupling oxidative phosphorylation in mitochondria, boosting energy consumption and heat production. BAM promotes fatty acid oxidation, raises the basal metabolic rate, and aids in fat reduction. It helps combat obesity by speeding up fat metabolism and lowering fat storage. Since obesity is a key factor in many metabolic diseases, BAM could offer a new approach to weight loss treatment.  As a mitochondrial uncoupler, the dosage of BAM15 usually depends on the purpose of the study and the individual's tolerance. The common dosage range is 10-20 mg per day, but the specific dosage should be adjusted according to professional physician or research recommendations. In terms of collocation, BAM15 can be used with some common weight loss auxiliary ingredients, such as green tea extract, caffeine, L-carnitine, etc. These ingredients help to further promote fat metabolism and increase energy expenditure. When using, it is recommended to gradually increase the dose in stages and ensure a balanced diet to avoid overstimulation and side effects. However, caution should be exercised when using it, and avoid overdose or use with other drugs and supplements to ensure safety and effectiveness. Before starting any new supplements, it is best to consult a doctor or professional.

Mitochondria

 

Factory Environment

The Xi'an Sonwu production facility is well-equipped, organized, and clean, with ample inventory. Led by the company, the researchers are committed to continuous product development. The laboratory features a well-maintained testing environment, state-of-the-art testing equipment, and a team of professional testers, all dedicated to delivering reliable data and ensuring a high-quality experience for customers.

factory

 

Certificates

certificates

 

Packaging

 

packaging

 

Logistics Record

shipping

In addition to guaranteeing product quality, the other most vital thing is clients can receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

logistics

 

Why Choose Us

Xi'an Sonwu has been in the import-export industry for over 10 years and has rich experience in both.

Xi'an Sonwu has 10 years of experience in product development, production, and sales.

Xi'an Sonwu has a professional team with a clear division of labor.

Xi'an Sonwu has professional laboratories and equipment to ensure high-quality products.

Third parties test products.

Xi'an Sonwu provides OEM service.

Xi'an Sonwu provides 7*24 customer service.

 

If you want to buy BAM 15 powder, feel free to contact Xi'an Sonwu.

E-mail: sales@sonwu.com

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