Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of olopatadine hydrochloride api in China. We warmly welcome yuo to wholesale bulk olopatadine hydrochloride api for sale here from our factory. Quality products and reasonable price are available.
What Is Olopatadine Hcl
Olopatadine hydrochloride API is a high-purity, stable-processable active pharmaceutical ingredient (API) for treating allergies. Belonging to the second-generation H1 receptor antagonists, it possesses highly selective anti-allergic activity with low central nervous system sedation. As an active pharmaceutical ingredient, it plays a crucial role in formulations and is an important raw material for treating allergic conjunctivitis, seasonal or perennial allergic rhinitis, and other allergic reactions. Olopatadine achieves rapid relief of allergy symptoms by selectively blocking histamine H1 receptors and inhibiting mast cell degranulation and the release of inflammatory mediators.
Olopatadine hcl powder is a perfect raw material for a variety of formulations, such as eye drops, oral tablets, capsules, and nasal sprays, due to its high purity, good solubility, stable crystal shape, and minimal negative effects on the central nervous system. Olatadine hydrochloride powder is widely utilized in clinical and pharmaceutical manufacturing industries because it is not only safer and less sedative than first-generation antihistamines.
Certificate Of Analysis
|
Item |
Specification |
Result |
|
Appearance |
White or off-white solid powder |
Conforms |
|
Identification |
HPLC retention time corresponds to the reference standard |
Conforms |
|
Melting point |
95ºC~105ºC |
101ºC~102ºC |
|
Loss on drying |
≤1.0% |
0.12% |
|
Heavy metals |
≤10ppm |
Conforms |
|
Residue on ignition |
≤0.1% |
0.05% |
|
Isomer |
≤0.15% |
ND |
|
Sulfated Ash |
≤0.05% |
0.01% |
|
Related substances |
Any single impurity: ≤0.50% |
0.45% |
|
|
Total impurities: ≤1.0% |
0.67% |
|
Assay |
98.0%~102.0% |
99.33% |
|
Conclusion |
Conforming to Enterprise Standard |
|
Where To Buy Olopatadine
Xi'an Sonwu Biotech Co. Ltd. has rich experience in the global trade and health industry. Insisting on faith-based and quality first is our company's principle. We strictly control product quality, which means selection starts from raw materials. Besides, we handle every detail and reduce the cost to the maximum extent, then our customers can get cost-effective products. Based on these, customers have given much good feedback to our products. So you can look for Xi'an Sonwu Biotech Co. Ltd. when you want to buy Olopatadine hcl powder.
Xi'an Sonwu completely makes sure of the product's quality, so samples can be supplied. Here is the quantity.
|
Form |
Sample Amount |
The Minimum of Quantity |
|
Powder |
100g |
100g |
Customers' Good Comment
What Is Olopatadine Hydrochloride Used For
Olopatadine hydrochloride API is an active pharmaceutical ingredient used in pharmaceutical formulations, primarily as a core component of anti-allergy medications. In pharmaceutical manufacturing, it is processed into various dosage forms, such as eye drops, oral tablets, capsules, or nasal sprays, for the treatment of various allergy-related conditions. Through these formulations, olopatadine hcl can relieve ocular allergy symptoms such as itchy eyes, redness, tearing, foreign body sensation, and burning sensation, while also alleviating nasal allergy symptoms such as sneezing, itchy nose, runny nose, and nasal congestion.
By pharmacologically blocking histamine H1 receptors, olopatadine hcl stops allergic reactions before they start. It also prevents mast cell degranulation and lowers the synthesis of histamine and other inflammatory mediators. This approach allows it to effectively lessen allergy symptoms whether administered systemically (e.g., orally) or topically (e.g., as eye drops).
Overall, the use of this raw material is not only to provide pharmacological activity, but also to play a core role in ensuring efficacy, stability and safety in formulation processing, making it an indispensable key component in the production of anti-allergy drugs.
The development of olopatadine hydrochloride powder took process optimization, dosage form compatibility, stability, and efficacy into full consideration. In order to satisfy the requirements of different dosage forms, such as hard capsule filling, tablet compression, ophthalmic drop dispersion, and nasal spray preparation, the team refined the powder's particle size, flowability, and compressibility during the R&D process.
What Should I Avoid When Using Olopatadine
When using this product, the following precautions should be taken to ensure the medication's safety and effectiveness:
1. Avoid overdose
Regardless of the form, strictly follow the dosage prescribed by your doctor or the instructions on the package insert. Overdose may increase the risk of side effects such as headache, dry mouth, or mild drowsiness.
2. Avoid concurrent use with other antihistamines
When other antihistamines (such loratadine, chlorpheniramine, etc.) are used concurrently, there may be adverse effects or synergistic effects. Avoid self-medication and use under a doctor's supervision.
3. Monitor liver and kidney function
Patients with liver or kidney dysfunction should adjust the dosage or monitor their drug response as directed by their doctor when using olopatadine hcl to avoid drug accumulation in the body leading to adverse reactions.
4. Avoid driving or operating machinery (caution)
Even though this product is a second-generation antihistamine with less sedative effects, some individuals may still feel a little sleepy or have trouble paying attention. Use caution when driving or using machinery, and pay attention to how your body responds to initial use or dose adjustments.
5. Use with caution in pregnant and lactating women
Pregnant or lactating women should use under the guidance of a physician to avoid potential risks to the fetus or infant.
6. Avoid prolonged and excessive use of eye drops
Prolonged use of ophthalmic olopatadine hydrochloride may mask symptoms of eye infections or cause local irritation. Use according to the prescribed course of treatment and have regular follow-up eye examinations.
7. Avoid mixing with strong acids, strong bases, or other incompatible solvents
If used in pharmaceutical manufacturing, olopatadine hydrochloride powder is sensitive to extreme pH levels or certain organic solvents. Strict compatibility control is required during formulation to prevent degradation or inactivation.
When using this material, the core principles are: use as prescribed or as directed in the instructions, avoid duplicate or excessive dosage, monitor liver and kidney function and special populations, and pay attention to drug compatibility. This will maximize the efficacy and safety of the drug.
What Are The Side Effects Of Olopatadine Hydrochloride
As a raw material powder, this product does not directly cause side effects. However, during formulation use or development, the potential side effects of its active ingredient can be summarized as follows, mainly based on its pharmacological effects and clinical experience:
1. Common Side Effects:
headache, sleepiness, and dry mouth.
Eye irritation (in eye drop formulations): When applied topically, there may be brief burning, stinging, or minor redness, but these normally go away fast.
2. Occasional or Rare Side Effects:
Gastrointestinal discomfort: Oral tablets or capsules may cause nausea, abdominal pain, or mild diarrhea.
Allergic reactions: In rare cases, individuals may experience allergic reactions to olopatadine hydrochloride or its excipients, manifesting as rash, itching, hives, and in severe cases, difficulty breathing.
Changes in vision or intraocular pressure (in ophthalmic formulations): Extremely rare with prolonged and excessive use of eye drops, but attention should be paid to whether blurred vision or increased intraocular pressure occurs.
3. Precautions for Special Populations:
Women who are pregnant or nursing: Self-use should be avoided as safety has not been completely proved. Oral formulations may cause drug buildup in the body, which raises the risk of adverse effects in patients with hepatic or renal impairment.
4. Powder Use Risks (Non-human Side Effects)
During formulation development or production, olopatadine hydrochloride powder itself may pose the following risks:
Inhalation irritation: Inhalation of the powder may irritate the respiratory tract or cause mild coughing. Handling should be done in well-ventilated areas or while wearing a protective mask.
Skin or eye contact: Contact with the powder may cause mild irritation. Gloves and goggles should be worn.
The potential side effects of olopatadine hydrochloride raw material powder used in vivo are mainly related to the pharmacological effects of antihistamines, including dry mouth, headache, mild drowsiness, and eye irritation. Occasional side effects may include gastrointestinal discomfort and allergic reactions. During formulation development and production, care should be taken to prevent inhalation and contact with skin and eyes to ensure safe handling.
Factory
1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.
2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.
Certificate
Package
Logistics Update
In addition to guaranteeing product quality, the other most vital thing is clients could receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.
Company's Profile
Xi'an Sonwu Biotech Co., Ltd is a professional Chinese manufacturer and products supplier. It was founded in 2012 and is located in the Hi-Tech Industrial Zone, Xi'an City, Shannxi Province, China. It pays all attention to the development, research, and production of food additives, plants, extract, APl, and other ingredients of health care products. The company supplies five kinds of raw material products: Anti-hair loss Powders, Nootropic, API, Muscle Building products, and Plant Extract. Xi'an Sonwu sincerely believes that the premise of great cooperation is the best service and good quality. So, welcome your inquiry.
And if you want to know the Olopatadine hydrochloride API price, please contact XI'an Sonwu.
Email: sales@sonwu.com
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