Xi'an Sonwu Biotech Co., Ltd. is one of the most professional manufacturers and suppliers of lithocholic acid powder in China. We warmly welcome yuo to wholesale bulk lithocholic acid powder for sale here from our factory. Quality products and reasonable price are available.
What Is Lithocholic Acid?
Lithocholic acid powder is an ordinary white powder commonly used to treat liver-related conditions. Lithocholic acid is a BA known as 3α-hydroxy-5β-cholan-24-oic acid or LCA. Cholic acids help emulsify and absorb dietary fats in the small intestine and are a natural product of cholesterol synthesis. Cholic acids(CA) have direct antimicrobial effects on gut microbes and an indirect impact through FXR-induced antimicrobial peptide production. CA,CDCA, DCA, and LCA are the primary bile acids associated with the gut microbiome.
LCA can be formed from chenodeoxycholate, usually in combination with glycine or taurine. It acts as a detergent to dissolve fat for absorption, so it is often used as a choleretic. As a professional manufacturer of LCA, Xi'an Sonwu is very popular among users for its high-quality products and competitive prices. If you need to buy, please feel free to contact Xi'an Sonwu.
COA
Where to Buy LCA？
Xi'an Sonwu Biotech Co. ltd. has rich global trade experience in the health industry. First, adhering to integrity-based quality is the tenet of Xi' an Sonwu. Xi' an Sonwu from the raw material selection, strict product quality control. In addition, Xi' an Sonwu handles every detail to minimize costs so customers get cost-effective products. On this basis, customers have given good feedback on the product. Therefore, when purchasing lithocholic acid powder, please choose Xi'an Sonwu Biotech Co. ltd.
Xi' an Sonwu can guarantee product quality and sample supply. Here is a quantitative reference.
Sample Quantity | The Minimum Quantity |
100g | 100g |
Customers' Comment
How Do You Dissolve LCA?
LCA is dissolved in organic solvents such as ethanol, DMSO, and dimethylformamide (DMF). The solubility of it is about 20 mg/ml in ethanol and DMSO and about 30 mg/ml in DMF. It is slightly soluble in aqueous buffers.
Is Lithocholic Acid a Bile Acid?
LCA is a monohydroxy secondary BA. This product is formed from the bacteria 7-dehydroxylated primary BA CDCA and secondary BA UDCA. So it is a bile acid.
The Medicinal Effect of LCA
Studies have found that LCA can kill bad cells and is harmless to normal nerve cells. Low concentrations of it sensitized BE(2)-m17 and SK-n-MCIXC cells to hydrogen peroxide-induced cell death. A specific concentration of LCA renders primary cultures of human neuronal cells somewhat resistant to this type of cell death. The findings suggest that it can kill not only by triggering intrinsic apoptotic cell death driven by mitochondrial outer membrane permeabilization and activation of the initiator CASPASE-9 but also by apoptotic cell death involving activation of the initiator CASPASE-8 external path to achieve.
What Does The LCA Do?
1. It can relieve cholecystitis.
2. It has a particular therapeutic effect on bronchitis and chronic bronchitis.
3. It can reduce blood fat and thus treat hyperlipidemia. Relieve cholecystitis.
4. It can protect gastrointestinal mucosa from mucosal damage. LCA can aid digestion and reduce diarrhea when patients have excretory dysfunction in the gallbladder. Oral LCA can partially replace the gallbladder in cholecystitis and bile deficiency cases and is usually well tolerated.
What Is the Cause of High LCA?
The liver of ordinary people usually synthesizes LCA. But when the body's liver cells are damaged, the liver will experience blockage and problems with metabolism, and the total LCA will rise. This condition affects not only the liver but also the development of the body.
1. Liver lesions.
2. Cholestasis syndrome is a significant cause of high LCA. Healthy people don't have this much of it in their blood. But when the liver cells are damaged, the inside and outside of the liver will be hindered. Thus, there will be abnormal CA metabolism, and the high LCA acid will increase.
3. high LCA belongs to a kind of liver cell lesion. High levels of LCA in the blood need to be checked out. The specific condition needs to be done after the examination can be understood.
4. Pregnancy is prone to jaundice this disease, which will lead to high LCA. Women during pregnancy, liver and intestinal circulation function will be damaged to a certain extent, so it is easier to cause this problem. Hormone levels also change during pregnancy, making cholestasis more likely.
LCA is a conjugated cholic acid synthesized by the liver's CA. It is one of the main components of CA, and its content change is of great value in diagnosing and treating liver diseases. High LCA is usually caused by conditions such as primary biliary cirrhosis and extrahepatic cholestasis caused by improper diet and emotional instability. Please go to the hospital for treatment in time.
What Effect does LCA have too low?
There are three reasons for low LCA.
1. It may be a substantial liver injury, and the reduction of CA synthesis is mainly light.
2. Gastrointestinal diseases may cause obstructed operation of CA.
3. It is mainly related to poor diet. An empty stomach without the Effect of eating stimulation will also lead to low, so do not care too much.
So don't worry. The elevation of lithic acid is a sign that there may be liver damage. A low level is no problem.
How Should Pregnancy Reduce LCA?
1. Diet
The diet is mainly light and low in salt. Eat more B-rich vegetables and whole grains, such as celery, broccoli, cabbage, carrots, peanuts, and beans.
2. Daily routine
Make sure you go to bed early, around 9 to 10 pm. Because 9 to 11 pm is a good time for liver and gallbladder repair and detoxification. Sleep is good for liver and gallbladder recovery.
3. Exercise
You can exercise for about one hour a day. Take a walk, do maternity exercises or move your arms and legs.
Because in the process of the regular diet, pregnant women are prone to abnormal problems such as acid reflux water, which will induce an indicator disease of LCA. Secondly, after pregnancy, their glutamic-pyruvic transaminase and other enzyme indicators will produce sure signs of increase but also impact their own stone cholic acid indicators.
Factory Environment
1. Xi'an Sonwu Biotech Co., Ltd has its factory, so it has adequate stock. Also, Xi'an Sonwu has a clean and tidy producing department with advanced equipment. With the lead of Xi'an Sonwu, researchers are constantly developing new products to meet customers' needs.
2. Xi'an Sonwu Biotech Co., Ltd has advanced test equipment and professional testers, which all show that Xi'an Sonwu aims to supply accurate and effective data and good service.
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The Latest Logistics Records
Besides guaranteeing the product's quality, the other most important thing is customers can receive the goods smoothly. So, Xi'an Sonwu supply all kinds of courier according to different need.
Why Choose us?
Pre-Sales Service：
1. OEM customization service
2. Support sample testing.
3. Enquiries will be answered within 24 hours.
4. Every batch of products is tested to ensure quality.
5. Provide packing list, bill of lading, commercial invoice, COA, and other supporting documents.
After-Sales Service:
1. Update logistics information timely.
2. All products with quality problems can be returned.
3. You can consult Xi'an Sonwu at any time about using the product.
How to Buy LCA?
Xi' an Sonwu Biotechnology Co., Ltd. is a production and sales as one technology-oriented enterprise and has been working on healthcare products for years. Xi' an Sonwu has been committed to providing customers with efficient, formal, and safe medical and biological products. With high-quality service and a rigorous working attitude, Songwu has won the recognition and trust of customers. If you want to buy lithocholic acid powder or other medical raw materials, please get in touch with Xi' an Sonwu. We will be in the best condition for your consultation.
E-mail: sales@sonwu.com
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